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When the 99 Mo decays, it forms pertechnetate TcO 4 −, which, because of its single charge, is less tightly bound to the alumina. Pulling normal saline solution through the column of immobilized 99 MoO 4 2− elutes the soluble 99m TcO 4 − , resulting in a saline solution containing the 99m Tc as the dissolved sodium salt of the pertechnetate .
4 is the starting material for most of the chemistry of technetium. Pertechnetate salts are usually colorless. [4] TcO − 4 is produced by oxidizing technetium with nitric acid or with hydrogen peroxide. The pertechnetate anion is similar to the permanganate anion but is a weaker oxidizing agent. It is tetrahedral and diamagnetic.
The metastable technetium-99m (99m Tc) is a short-lived (half-life about 6 hours) nuclear isomer used in nuclear medicine, produced from molybdenum-99. It decays by isomeric transition to technetium-99, a desirable characteristic, since the very long half-life and type of decay of technetium-99 imposes little further radiation burden on the body.
The typical procedure involves use of Technetium-99m colloid, or in some cases pertechnetate. The colloid is prepared with an activity of approximately 20 megabecquerels in 1 millilitre (ml). Patients place their head in a support and chin rest and a single drop of 0.01 ml is delivered to each eye.
A technetium-99m pertechnetate scan, also called Meckel scan or nuclear scintigraphy scan, is the investigation of choice to diagnose Meckel's diverticula in children. This scan detects gastric mucosa ; since approximately 50% of symptomatic Meckel's diverticula have ectopic gastric or pancreatic cells contained within them, [ 24 ] this is ...
The MUGA scan is performed by labeling the patient's red blood pool with a radioactive tracer, technetium-99m-pertechnetate (Tc-99m), and measuring radioactivity over the anterior chest as the radioactive blood flows through the large vessels and the heart chambers. [citation needed]
Pertechnetate is one of the most available forms of technetium. It is structurally related to permanganate. The most prevalent form of technetium that is easily accessible is sodium pertechnetate, Na[TcO 4]. The majority of this material is produced by radioactive decay from [99 MoO 4] 2−: [1] [2] [99 MoO 4] 2− → [99m TcO 4] − + e −
Technetium 99m Tc albumin aggregated (99m Tc-MAA) is an injectable radiopharmaceutical used in nuclear medicine. It consists of a sterile aqueous suspension of Technetium-99m (99m Tc) labeled to human albumin aggregate particles. It is commonly used for lung perfusion scanning.