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The U.S. Food and Drug Administration has approved Pfizer's newest drug on the migraine market, Zavzpret (zavegepant) -- the first and only migraine treatment of its kind to be offered in nasal spray.
Zavzpret is a new nasal spray to treat migraine headaches in adults. But how does the medication work and who should try the new FDA-approved medication?
Academics said their findings are ‘important’ considering the higher costs of new treatments. New migraine drugs ‘comparable to paracetamol’, researchers suggest Skip to main content
Rescue treatment involves acute symptomatic control with medication. [4] Recommendations for rescue therapy of migraine include: (1) migraine-specific agents such as triptans, CGRP antagonists, or ditans for patients with severe headaches or for headaches that respond poorly to analgesics, (2) non-oral (typically nasal or injection) route of administration for patients with vomiting, (3) avoid ...
Examples of specific antimigraine drug classes include triptans (first line option), ergot alkaloids, ditans and gepants. Migraines can also be treated with unspecific analgesics such as nonsteroidal anti-inflammatory drugs (NSAIDs) or acetaminophen. Opioids are not recommended for treatment of migraines.
In 2018, the first medication of a new class of drugs specifically designed for migraine prevention called calcitonin gene-related peptide receptor antagonists (CGRPs) was approved by the FDA. [20] As of July 2023, the FDA has approved eight drugs that act on the CGRP system for use in the treatment of migraine. [21]
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