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Dahl's sign (also Thinker's sign or Target sign) [1] is a clinical sign in which areas of darkened (hyperpigmentation) and thickened (hyperkeratotic) skin are seen on the lower thighs and elbows. [2] It occurs in patients with longstanding severe chronic obstructive pulmonary disease .
Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by chronic respiratory symptoms and airflow limitation. [8] GOLD 2024 defined COPD as a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea or shortness of breath, cough, sputum production or exacerbations) due to abnormalities of the airways (bronchitis ...
Many people with chronic obstructive pulmonary disease have a low partial pressure of oxygen in the blood and high partial pressure of carbon dioxide.Treatment with supplemental oxygen may improve their well-being; alternatively, in some this can lead to the adverse effect of elevating the carbon dioxide content in the blood (hypercapnia) to levels that may become toxic.
COPD is a risk factor for coronary artery disease (CAD)—a type of heart disease caused by buildup of plaque in the arteries, says Dr. Attaway. Research suggests that CAD is a leading cause of ...
Many patients eventually require oxygen supplementation at home. In severe cases that are difficult to control, chronic treatment with oral corticosteroids may be necessary, although this is fraught with significant side effects. COPD is generally irreversible although lung function can partially recover if the patient stops smoking.
It’s important to speak with a doctor about personalizing exercise for your specific form of COPD. The disease affects people at different fitness levels, and patients with COPD may have ...
The incidence varies depending on which definition is used, but definitions by Anthonisen et al. [23] the typical COPD patient averages two to three AECB episodes per year. [24] With a COPD prevalence of more than 12 million (possibly 24 million including undiagnosed ones) in the United States, [ 25 ] there are at least 30 million incidences of ...
When associated with significant airflow limitation, emphysema is a major subtype of chronic obstructive pulmonary disease (COPD), a progressive lung disease characterized by long-term breathing problems and poor airflow. [10] [11] Without COPD, the finding of emphysema on a CT lung scan still confers a higher mortality risk in tobacco smokers ...
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