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Dibenzo-1,4-dioxin, also dibenzodioxin or dibenzo-p-dioxin (dibenzo-para-dioxin), is a polycyclic heterocyclic organic compound in which two benzene rings are connected by a 1,4-dioxin ring. Its molecular formula is C 12 H 8 O 2. The two oxygen atoms occupy opposite (para-) positions in the six-membered dioxin ring.
Mometasone, also known as mometasone furoate, is a steroid (specifically, a glucocorticoid) medication used to treat certain skin conditions, hay fever, and asthma. [ 10 ] [ 11 ] [ 12 ] Specifically it is used to prevent rather than treat asthma attacks. [ 10 ]
The oral LD50 for guinea pigs is as low as 0.5 to 2 μg/kg body weight, whereas the oral LD50 for hamsters can be as high as 1 to 5 mg/kg body weight, a difference of as much as thousandfold or more, and even among rat strains there may be thousandfold differences.
Dibenzo-1,4-dioxin, also known as dibenzodioxin or dibenzo-p-dioxin (molecular formula C 12 H 8 O 2), in which two benzene rings are connected through two oxygen atoms. That is the parent compound of the dioxins (see next in which the dioxins comprise a key part of the class)
1,4-Dioxin (also referred as dioxin or p-dioxin) is a heterocyclic, organic, non-aromatic [2] compound with the chemical formula C 4 H 4 O 2. There is an isomeric form of 1,4-dioxin, 1,2-dioxin (or o -dioxin). 1,2-Dioxin is very unstable due to its peroxide -like characteristics.
For treating atopic dermatitis, newer (second generation) corticosteroids, such as fluticasone propionate and mometasone furoate, are more effective and safer than older ones. They are also generally safe and do not cause skin thinning when used intermittently to treat atopic dermatitis flare-ups.
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The rate constant for the vapor phase reaction of heptachlorodibenzo-p-dioxin with photochemically produced hydroxyl radicals has been estimated to be 1.3x10 −12 cu cm/molecule-sec at 25 °C which corresponds to an atmospheric half-life of 12.3 days at an atmospheric concentration of 5x10 5 hydroxyl radicals per cu cm. [13]