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  2. Mirtazapine - Wikipedia

    en.wikipedia.org/wiki/Mirtazapine

    Mirtazapine is a very strong H 1 receptor antagonist and, as a result, it can cause powerful sedative and hypnotic effects. [11] A single 15 mg dose of mirtazapine to healthy volunteers has been found to result in over 80% occupancy of the H 1 receptor and to induce intense sleepiness. [92]

  3. Quetiapine - Wikipedia

    en.wikipedia.org/wiki/Quetiapine

    Doses of quetiapine used for insomnia have ranged from 12.5 to 800 mg, with low doses of 25 to 200 mg being the most typical. [ 38 ] [ 31 ] [ 32 ] Regardless of the dose used, some of the more serious adverse effects may still possibly occur at the lower dosing ranges, such as dyslipidemia and neutropenia .

  4. Esmirtazapine - Wikipedia

    en.wikipedia.org/wiki/Esmirtazapine

    [8] [1] Unlike low-dose mirtazapine, the half life (10 hours) is short enough that next-day sedation may be manageable, however, for people with CYP2D6 polymorphisms, which constitute a sizable fraction of the population, the half-life is expected to be quite a bit longer. Merck researchers claimed that the incidence of next-day sedation was ...

  5. Switching Antidepressants: Safety, Side Effects & Other ... - AOL

    www.aol.com/switching-antidepressants-safety...

    Changing your dosage or abruptly stopping your medication could cause you to experience antidepressant withdrawal symptoms like those electric shocks — also known as “brain zaps.” Switching ...

  6. Are Wellbutrin Dosages Different For Anxiety And Depression?

    www.aol.com/lifestyle/wellbutrin-dosages...

    The saying “knowledge is power” applies well in certain situations — like becoming a leader in your field of expertise or knowing the best places to eat (we all have different skills).

  7. H1 antagonist - Wikipedia

    en.wikipedia.org/wiki/H1_antagonist

    No (at low doses) Mirtazapine: 7.5–15 mg 2 hours 20–40 hours CYP2D6, others No Quetiapine e: 25–200 mg 1.5 hours 7 hours d: CYP3A4 No (at low doses) Footnotes: a = For sleep/sedation. b = In adults. c Active metabolite nordoxepin half-life is 31 hours. d Active metabolite norquetiapine half-life is 9–12 hours. e Not recommended per ...

  8. Noradrenergic and specific serotonergic antidepressant

    en.wikipedia.org/wiki/Noradrenergic_and_specific...

    Chemical structure of the prototypical NaSSA mirtazapine (original brand name Remeron). Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants. [1]

  9. Can antidepressants speed up cognitive decline in dementia? - AOL

    www.aol.com/lifestyle/antidepressants-speed...

    The researchers studied nearly 19,000 people diagnosed with dementia, and around 23% received antidepressants as a treatment for depression. The study showed that cognitive decline was worse in ...

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