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  2. Mirtazapine - Wikipedia

    en.wikipedia.org/wiki/Mirtazapine

    Mirtazapine is a very strong H 1 receptor antagonist and, as a result, it can cause powerful sedative and hypnotic effects. [11] A single 15 mg dose of mirtazapine to healthy volunteers has been found to result in over 80% occupancy of the H 1 receptor and to induce intense sleepiness. [92]

  3. Your Guide to the 6 Most Common Types of Depression ... - AOL

    www.aol.com/6-types-depression-medications...

    It’s also commonly used as a low-dose sleeping pill to help with acute and chronic insomnia. ... but mirtazapine (Remeron) wins the “Most Popular” superlative. In addition to depression ...

  4. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]

  5. Noradrenergic and specific serotonergic antidepressant

    en.wikipedia.org/wiki/Noradrenergic_and_specific...

    Chemical structure of the prototypical NaSSA mirtazapine (original brand name Remeron). Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants. [1]

  6. Esmirtazapine - Wikipedia

    en.wikipedia.org/wiki/Esmirtazapine

    [8] [1] Unlike low-dose mirtazapine, the half life (10 hours) is short enough that next-day sedation may be manageable, however, for people with CYP2D6 polymorphisms, which constitute a sizable fraction of the population, the half-life is expected to be quite a bit longer. Merck researchers claimed that the incidence of next-day sedation was ...

  7. List of benzodiazepines - Wikipedia

    en.wikipedia.org/wiki/List_of_benzodiazepines

    Low IC 50 or high pIC 50 values indicate tighter binding (pIC 50 of 8.0 = IC 50 of 10nM, pIC 50 of 9.0 = IC 50 of 1nM, etc.) These are non subtype selective IC 50 values averaged across all GABA A receptor subtypes , so subtype selective compounds with strong binding at one subtype but weak at others will appear unusually weak due to averaging ...

  8. These are the top 100 Black Friday deals, according to Walmart

    www.aol.com/lifestyle/these-are-the-top-100...

    The deals are just as good during Black Friday weekend as they were on the day itself. AirPods are still at the lowest price of the year, and you can still get a new high-quality TV for less than ...

  9. Serotonin–norepinephrine reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Serotonin–norepinephrine...

    The reuptake effects of venlafaxine are dose-dependent. At low doses (<150 mg/day), it acts only on serotonergic transmission. At moderate doses (>150 mg/day), it acts on serotonergic and noradrenergic systems, whereas at high doses (>300 mg/day), it also affects dopaminergic neurotransmission. [ 22 ]

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