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These can help prevent gout flares and further complications. According to the American College of Rheumatology guidelines , allopurinol is the first-line medication for lowering uric acid levels.
“Gout is a common type of arthritis that can be extremely painful,” Dr. Tochi Iroku-Malize, board chair of the American Academy of Family Physicians, tells Yahoo Life. “Symptoms include ...
Do you sometimes have severe, unexplained pain in your joints, particularly in your big toe, ankle, or knee? The post Managing Out-of-Control Chronic Gout: Going Beyond Oral Treatments appeared ...
Gout presenting as slight redness in the metatarsophalangeal joint of the big toe. Gout can present in several ways, although the most common is a recurrent attack of acute inflammatory arthritis (a red, tender, hot, swollen joint). [4] The metatarsophalangeal joint at the base of the big toe is affected most often, accounting for half of cases ...
In gout, inflammation in joints results from the precipitation of uric acid as needle-like crystals of monosodium urate in and around synovial fluid and soft tissues of joints. [15] These crystal deposits cause inflammatory arthritis, which is initiated and sustained by mechanisms involving various proinflammatory mediators, such as cytokines. [15]
Uricosurics are often used in the treatment of gout, a disease in which uric acid crystals form deposits in the joints. By decreasing plasma uric acid levels, help dissolve these crystals, while limiting the formation of new ones. However, the increased uric acid levels in urine can contribute to kidney stones.
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