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Over the last 25 years, (ED) medications such as Viagra and others have become common and normal pieces of bedroom tool kit. These little pills have helped hundreds of millions of men all over the ...
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
In the ‘80s, researchers set out to test a medication called sildenafil citrate for treating high blood pressure and angina (chest pain) from heart disease.
Generic sildenafil (and brand-name Viagra) is a medication for the treatment of ED, Raynaud’s phenomenon, and pulmonary arterial hypertension. To understand how Viagra works, we need to look at ...
Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9] It is unclear if it is effective for treating sexual dysfunction in females. [8]
Many drugs can cause loss of libido as a side effect. [ 12 ] Since a partial cause of the refractory period is the inhibition of dopamine by an orgasm-induced secretion of prolactin , [ 13 ] such potent dopamine receptor agonists as cabergoline may help achieve multiple orgasms as well as the retention of sexual arousal for longer periods of time.
Viagra could lead to more serious side effects, such as: Priapism (a painful, long-lasting arousal) Vision loss. Chest pain. Flu-like symptoms. Heart attack. Stroke. Dizziness. Sudden low blood ...
Viagra (or sildenafil) lasts three to five hours after it’s consumed. Cialis (tadalafil) has a half-life of 17.5 hours, meaning this drug lasts up to 36 hours after it’s consumed.