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Alendronic acid, sold under the brand name Fosamax among others, is a bisphosphonate medication used to treat osteoporosis and Paget's disease of bone. [4] It is taken by mouth. [4] Use is often recommended together with vitamin D, calcium supplementation, and lifestyle changes. [4]
Surfactant therapy is the medical administration of pulmonary surfactant that is derived from outside of the body. Pulmonary surfactant is a soap-like chemical synthesized by type II alveolar pneumocytes and is of various lipids (80% phospholipids, 5-10% cholesterol, and ∼10% surfactant-associated proteins).
It is an effective anabolic (promoting bone formation) agent [15] used in the treatment of some forms of osteoporosis. [13] [16] Teriparatide is a recombinant human parathyroid hormone analog (PTH 1-34). [13] It has an identical sequence to the 34 N-terminal amino acids of the 84-amino acid human parathyroid hormone. [13]
Zoledronic acid is also indicated for the treatment and prevention of postmenopausal osteoporosis; the treatment to increase bone mass in men with osteoporosis; the treatment and prevention of glucocorticoid-induced osteoporosis; the treatment of Paget’s disease of bone in men and women.
A 24-week randomized trial was conducted in postmenopausal women with osteoporosis (n=222) assessing bone mass density (BMD) changes as the primary endpoint. [17] Significant BMD increase at doses of 40 and 80 mcg were found in the lumbar spine , femur and hips of abaloparatide-treated participants compared to placebo .
The US National Osteoporosis Foundation recommends pharmacologic treatment for patients with hip or spine fracture thought to be related to osteoporosis, those with BMD 2.5 SD or more below the young normal mean (T-score -2.5 or below), and those with BMD between 1 and 2.5 SD below normal mean whose 10-year risk, using FRAX, for hip fracture is ...
On e-commerce platforms like Etsy, TikTok Shop, eBay and Redbubble, sellers are hawking merchandise featuring designs inspired by the fatal shooting of UnitedHealthcare CEO Brian Thompson.
They are used for the treatment of osteoporosis and other bone disorders that cause bone fragility and diseases where bone resorption is excessive. Osteoporosis is common in post-menopausal women and patients in corticosteroid treatment where biphosphonates have been proven a valuable treatment and also used successfully against Paget's disease ...
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