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Metoprolol is classified as a moderately lipophilic beta blocker. [37] More lipophilic beta blockers tend to cross the blood–brain barrier more readily, with greater potential for effects in the central nervous system as well as associated neuropsychiatric side effects. [37] Metoprolol binds mainly to human serum albumin with an unbound ...
Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke, heart failure, kidney failure and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34% and of ischaemic heart disease by 21%, and can reduce the likelihood of dementia ...
For most people, recommendations are to reduce blood pressure to less than or equal to somewhere between 140/90 mmHg and 160/100 mmHg. [2] In general, for people with elevated blood pressure, attempting to achieve lower levels of blood pressure than the recommended 140/90 mmHg will create more harm than benefits, [3] in particular for older people. [4]
“Although high blood pressure typically causes no symptoms and people may feel perfectly well, long-term high blood pressure has been conclusively shown to damage internal organs, particularly ...
[22] [23] This results an increase in heart rate and blood pressure, therefore increasing myocardial oxygen demand. [ 23 ] [ 22 ] Beta blockers competitively inhibit catecholamines acting on the β 1 -adrenergic receptors, thus reducing these detrimental effects and resulting in reduced myocardial oxygen consumption and demand.
The good news is there are things you can do when you wake up that can help manage high blood pressure, like physical activity, eating a balanced breakfast, drinking water, practicing relaxation ...
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