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2. Viagra may help prevent dementia by boosting brain blood flow

   www.aol.com/viagra-may-help-prevent-dementia...

   In this study, he explained, “sildenafil was associated with a 69% reduction in the risk of developing Alzheimer’s disease.” Tackling lifestyle risk factors for dementia

3. Sildenafil - Wikipedia

   en.wikipedia.org/wiki/Sildenafil

   Sildenafil's brand name, Viagra, is widely recognized in popular culture, and the drug's association with treating erectile dysfunction has led to its recreational use. [33] The reasons behind such use include the belief that the drug increases libido, improves sexual performance, [ 33 ] or permanently increases penis size. [ 34 ]

4. Viagra: What It Treats & Its Side Effects ( Plus What It Was ...

   www.aol.com/viagra-treats-side-effects-plus...

   Sildenafil Drug Interactions. A word on sildenafil drug interactions: Mixing antihypertensive prescription drugs (hypertension meds) with Viagra may cause low blood pressure. Since the medication ...

5. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

   www.aol.com/ed-pill-guide-everything-know...

   Viagra (or sildenafil) lasts three to five hours after it’s consumed. Cialis (tadalafil) has a half-life of 17.5 hours, meaning this drug lasts up to 36 hours after it’s consumed.

6. PDE5 inhibitor - Wikipedia

   en.wikipedia.org/wiki/PDE5_inhibitor

   Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

7. Discovery and development of phosphodiesterase 5 inhibitors

   en.wikipedia.org/wiki/Discovery_and_development...

   Sildenafil is a prototype of PDE5 inhibitors that Pfizer launched as Viagra. It was approved by the Food and Drug Administration (FDA) in 1998 as the first oral medicine for erectile dysfunction. Later, in the year 2005, it was approved for the treatment of pulmonary arterial hypertension. [2]