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Lubiprostone received approval from the Food and Drug Administration in 2008, to treat irritable bowel syndrome with constipation (IBS-C), [7] and in 2013, for the treatment of opioid-induced constipation in adults with chronic noncancer pain. [4] It is available as a generic medication. [8]
Medicare Part D generally includes coverage for prescription drugs such as ... specifically to treat irritable bowel syndrome with constipation and chronic idiopathic constipation in adults.
Lactulose is a non-absorbable sugar used in the treatment of constipation and hepatic encephalopathy. [3] [4] It is administered orally for constipation, and either orally or rectally for hepatic encephalopathy. [3] It generally begins working after 8–12 hours, but may take up to 2 days to improve constipation. [1] [2]
In the European Economic Area, prucalopride was originally approved for the symptomatic treatment of chronic constipation in women in whom laxatives fail to provide adequate relief. [29] Subsequently, it has been approved by the European Commission for use in adults – that is, including male patients – for the same indication. [32]
Linaclotide, (sold under the brand name Linzess in the US and Mexico, and as Constella elsewhere) [6] is a drug used to treat irritable bowel syndrome with constipation and chronic constipation with no known cause.
Secondary constipation, which is due to another cause, such as chronic conditions, like Type 2 diabetes, poor dietary choices or neurological conditions that may impact intestinal motility
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