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Sjögren's syndrome is associated with a number of other medical conditions, many of which are autoimmune or rheumatic disorders, such as celiac disease, [24] [25] fibromyalgia, systemic lupus erythematosus (lupus), autoimmune thyroiditis, multiple sclerosis and spondyloarthropathy, [26] and several malignancies, principally non-Hodgkin lymphoma.
About 20–25% of individuals with a chronic general medical condition will develop major depression. [5] Common comorbid disorders include eating disorders, substance-related disorders, panic disorder, and obsessive-compulsive disorder. Up to 25% of people who experience a major depressive episode have a pre-existing dysthymic disorder. [5]
Small stature, mild to severe intellectual disability and dysarthria (slow, imprecise speech) are usually present. Various skeletal abnormalities (e.g., curvature of the spine) and hypergonadotropic hypogonadism often occur. Muscle weakness is progressive, but life expectancy is near normal.
Neurological problems – this can often cause mild paralysis in the legs; Mild to moderate intellectual disability. Often associated ocular features, which include pigmentary changes in the retina. The usual presentation of crystalline maculopathy is from the age of 1–2 years onwards. [citation needed]
Psychiatric medication is also widely used to treat mental disorders. These are licensed psychoactive drugs usually prescribed by a psychiatrist or family doctor. There are several main groups. Antidepressants are used for the treatment of clinical depression as well as often for anxiety and other disorders. [30]
A revision of DSM-5, titled DSM-5-TR, was published in March 2022, updating diagnostic criteria and ICD-10-CM codes. [52] The diagnostic criteria for avoidant/restrictive food intake disorder were changed, [ 53 ] [ 54 ] along with adding entries for prolonged grief disorder , unspecified mood disorder and stimulant-induced mild neurocognitive ...
Treatment of minor depressive disorder has not been studied as extensively as major depressive disorder. Although there are often similarities in the treatments used, there are also differences in what may work better for the treatment of minor depressive disorder. Some third-party payers do not pay to cover treatment for minor depressive disorder.
Serotonergic-noradrenergic antidepressant drugs may have a modest efficacy advantage compared to SSRIs in treating major depressive disorder (MDD), [43] but are slightly less well tolerated. [44] Further research is needed to examine the possible differences of efficacy in specific MDD sub-populations or for specific MDD symptoms, between these ...
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