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Fluorouracil (5-FU, 5-fluorouracil), sold under the brand name Adrucil among others, is a cytotoxic chemotherapy medication used to treat cancer. [3] By intravenous injection it is used for treatment of colorectal cancer , oesophageal cancer , stomach cancer , pancreatic cancer , breast cancer , and cervical cancer . [ 3 ]
This ensures quick and firm engagement without being too fast for the drivetrain to handle, while also allowing the clutch to quickly disengage. BMW has used clutch delay valves on the E39 and E46 models, and others, from 1997. These valves have been unpopular with some drivers and are sometimes removed in favour of a conventional clutch action ...
Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.
The dose schedule given every two weeks is as follows: [5] Day 1–2: Oxaliplatin 100 mg/m 2 IV infusion, given as a 120 minutes IV infusion in 500 mL D5W, concurrent with leucovorin 400 mg/m 2 (or levoleucovorin 200 mg/m 2) IV infusion, followed by 5-FU 400 mg/m 2 IV bolus, followed by 46-hour 5-FU infusion (2400 mg/m 2 for first two cycles, and may be increased to 3000 mg/m 2 if tolerated by ...
The internal clutch actuator in a semi-automatic transmission can be powered by either hydraulic, pneumatic, or electric means. [ 6 ] [ 7 ] Later examples of clutchless manual transmissions used in road cars include the Saab Sensonic transmission, used in the 900 NG , and the Ferrari Valeo auto-manual transmission, used in the Mondial T .
Citroën combined a freewheel and a centrifugal clutch to make the so-called 'TraffiClutch', which let the driver start, stop, and change the lower gears without using the clutch. This was an option on Citroën 2CVs and its derivatives and, as the name implied, was marketed as a benefit for driving in congested urban areas.
Cyclophosphamide Methotrexate Fluorouracil (CMF) is a commonly used regimen of breast cancer chemotherapy that combines three anti-cancer agents: cyclophosphamide, methotrexate, and 5-fluorouracil (5-FU).