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Protein kinase B (PKB), also known as Akt, is the collective name of a set of three serine/threonine-specific protein kinases that play key roles in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription, and cell migration.
RAC(Rho family)-alpha serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT1 gene.This enzyme belongs to the AKT subfamily of serine/threonine kinases that contain SH2 (Src homology 2-like) protein domains. [5]
It was originally prepared from tetramethylthiourea via S-methylation and amination, but alternative methods start from cyanogen iodide. [3] Uses
Under oxidative stress, miR-126 promotes Akt/PKB signaling pathway activation. This increases the biological function of cells under oxidative stress. This is important in endothelial progenitor cell transplantation to treat acute myocardial infarction (AMI) and may serve as a new therapeutic approach to treat AMI.
Free energy is made up of an enthalpy term and an entropy term. [11] = The standard enthalpy change can be determined by calorimetry or by using the van 't Hoff equation, though the calorimetric method is preferable. When both the standard enthalpy change and acid dissociation constant have been determined, the standard entropy change is easily ...
blood chemistry profile: BCX BCx: blood culture: BDR: Background Diabetic Retinopathy: BBMF "bone break, me fix" (orthopedic consent form) BD: bipolar disorder twice a day (from Latin bis in die) BDD: body dysmorphic disorder: BDI: Beck Depression Inventory: BDS: two times a day (from Latin bis die sumendus) BE: barium enema base excess: BEAM
In chemistry, biochemistry, and pharmacology, a dissociation constant (K D) is a specific type of equilibrium constant that measures the propensity of a larger object to separate (dissociate) reversibly into smaller components, as when a complex falls apart into its component molecules, or when a salt splits up into its component ions.
Also acid ionization constant or acidity constant. A quantitative measure of the strength of an acid in solution expressed as an equilibrium constant for a chemical dissociation reaction in the context of acid-base reactions. It is often given as its base-10 cologarithm, p K a. acid–base extraction A chemical reaction in which chemical species are separated from other acids and bases. acid ...