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  2. Sirolimus - Wikipedia

    en.wikipedia.org/wiki/Sirolimus

    Sirolimus, also known as rapamycin and sold under the brand name Rapamune among others, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection, treat a rare lung disease called lymphangioleiomyomatosis, and treat perivascular epithelioid cell tumour (PEComa).

  3. mTOR inhibitors - Wikipedia

    en.wikipedia.org/wiki/MTOR_inhibitors

    mTOR inhibitors are a class of drugs used to treat several human diseases, including cancer, autoimmune diseases, and neurodegeneration. They function by inhibiting the mammalian target of rapamycin (mTOR) (also known as the mechanistic target of rapamycin), which is a serine/threonine-specific protein kinase that belongs to the family of phosphatidylinositol-3 kinase (PI3K) related kinases ...

  4. Immunosuppressive drug - Wikipedia

    en.wikipedia.org/wiki/Immunosuppressive_drug

    Sirolimus (rapamycin, trade name Rapamune) is a macrolide lactone, produced by the actinomycete bacterium Streptomyces hygroscopicus. It is used to prevent rejection reactions. Although it is a structural analogue of tacrolimus, it acts somewhat differently and has different side-effects.

  5. FDA approves new pain medication as an alternative to ... - AOL

    www.aol.com/fda-approves-pain-medication...

    The drug, suzetrigine, received the FDA's official stamp of approval Thursday to be sold as a 50-milligram prescription pill taken every 12 hours, according to a press release.

  6. Lymphangioleiomyomatosis - Wikipedia

    en.wikipedia.org/wiki/Lymphangioleiomyomatosis

    The benefits of sirolimus only persist while treatment continues. The safety of long term therapy has not been studied. [citation needed] Potential side effects from mTOR inhibitors include swelling in the ankles, acne, oral ulcers, dyspepsia, diarrhea, elevation of cholesterol and triglycerides, hypertension and headache. Sirolimus pneumonitis ...

  7. 6 Common Side Effects from Taking a GLP-1 Medication ... - AOL

    www.aol.com/6-common-side-effects-taking...

    These side effects might be common, but there are things you can do if they’re impacting your daily life. 6 Common Side Effects from Taking a GLP-1 Medication—and How to Manage Them Skip to ...

  8. Surendra Nath Sehgal - Wikipedia

    en.wikipedia.org/wiki/Surendra_Nath_Sehgal

    Surendra Nath Sehgal (1932–2003) was an Indian-Canadian-American microbiologist and pharmaceutical scientist most widely known for his discovery and development of Rapamycin (Sirolimus), a immunosuppressant drug widely used in organ transplantation. Rapamycin has also attracted attention as a potential anti-cancer [1] and anti-aging drug. [2]

  9. The best Dutch ovens of 2025, tested by AOL

    www.aol.com/lifestyle/best-dutch-ovens-190855583...

    There are a wide range of Dutch ovens out there today, and they vary in size, material, and price. To help you find the best option to add to your kitchen, we spent months testing a total of 10 ...

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