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Hypothyroidism (also called underactive thyroid, low thyroid or hypothyreosis) is a disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormones. [3] It can cause a number of symptoms, such as poor ability to tolerate cold , extreme fatigue, muscle aches , constipation , slow heart rate , depression , and ...
Furthermore, reviewing their medications and possible dietary supplements is important, as several medications can affect thyroid hormone levels. [14] Levothyroxine is also used to treat subclinical hypothyroidism, which is defined by an elevated TSH level and a normal-range free T 4 level without symptoms. [14]
Thyroid diseases are highly prevalent worldwide, [10] [11] [12] and treatment varies based on the disorder. Levothyroxine is the mainstay of treatment for people with hypothyroidism, [13] while people with hyperthyroidism caused by Graves' disease can be managed with iodine therapy, antithyroid medication, or surgical removal of the thyroid ...
Commonly prescribed thyroid drug levothyroxine was linked with bone mass and bone density loss in a cohort of older adults in a recent study. ... (indicating an underactive thyroid), fatigue ...
Medication. Some medications can lower testosterone. ... Also known as an underactive thyroid, hypothyroidism happens when your thyroid gland doesn't produce enough thyroid hormones.
In hypothyroidism, your thyroid gland is underactive, and your metabolism slows down, sometimes leaving you with chills. Other common symptoms include tiredness, weight gain, constipation, dry ...
They inhibit release of thyroid hormones by the thyroid gland.The most studied drug in this class is lithium, which inhibits thyroid hormone secretion by inhibiting iodotyrosine coupling, thyroidal iodide uptake, and alteration in structure of thyroglobulin, [10] a protein which acts as a substrate for the synthesis of thyroid hormones and storage of inactive forms of T3, T4 and iodine within ...
[1] [2] Some thyromimetic drugs are selective for various of these receptors over others, enabling more targeted effects and reducing toxicity. Thyromimetics selective for TRβ—including eprotirome , [ 3 ] sobetirome , [ 4 ] resmetirom , [ 5 ] and the prodrug VK2809 —have been investigated for the treatment of non-alcoholic fatty liver ...
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