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The free radical theory of aging states that organisms age because cells accumulate free radical damage over time. [ 1 ] A free radical is any atom or molecule that has a single unpaired electron in an outer shell. [ 2 ] While a few free radicals such as melanin are not chemically reactive, most biologically relevant free radicals are highly ...
Biogerontology is the sub-field of gerontology concerned with the biological aging process, its evolutionary origins, and potential means to intervene in the process. The term "biogerontology" was coined by S. Rattan, and came in regular use with the start of the journal Biogerontology in 2000. It involves interdisciplinary research on the ...
For the context of control theory, see stochastic control. Stochastic optimization (SO) are optimization methods that generate and use random variables. For stochastic optimization problems, the objective functions or constraints are random. Stochastic optimization also include methods with random iterates.
The Gompertz–Makeham law of mortality describes the age dynamics of human mortality rather accurately in the age window from about 30 to 80 years of age. At more advanced ages, some studies have found that death rates increase more slowly – a phenomenon known as the late-life mortality deceleration [2] – but more recent studies disagree.
Stochastic (/ stəˈkæstɪk /; from Ancient Greek στόχος (stókhos) 'aim, guess') [ 1 ] is the property of being well-described by a random probability distribution. [ 1 ] Stochasticity and randomness are distinct, in that the former refers to a modeling approach and the latter refers to phenomena; these terms are often used synonymously.
Filtering problem (stochastic processes) In the theory of stochastic processes, filtering describes the problem of determining the state of a system from an incomplete and potentially noisy set of observations. While originally motivated by problems in engineering, filtering found applications in many fields from signal processing to finance.
In mathematics, the theory of optimal stopping[1][2] or early stopping[3] is concerned with the problem of choosing a time to take a particular action, in order to maximise an expected reward or minimise an expected cost. Optimal stopping problems can be found in areas of statistics, economics, and mathematical finance (related to the pricing ...
The Hayflick limit is the limit on cell replication imposed by the shortening of telomeres with each division. This end stage is known as cellular senescence. The Hayflick limit has been found to correlate with the length of the telomeric region at the end of chromosomes. During the process of DNA replication of a chromosome, small segments of ...