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Darbepoetin is marketed by Amgen under the trade name Aranesp. The medication was approved in September 2001, by the US Food and Drug Administration for treatment of anemia in patients with chronic kidney failure by intravenous or subcutaneous injection. [ 4 ]
Bioavailability is 91% at the standard subcutaneous dose but 24% at the standard oral dose; the standard oral dose is higher to partially compensate for incomplete bioavailability. [ 5 ] [ 18 ] It binds to plasma proteins at a rate of 99.5%; it has a low volume of distribution (9 L/kg) and is thus not extensively absorbed.
The 2020 Cochrane Anaesthesia Review Group review of erythropoietin (EPO) plus iron versus control treatment including placebo or iron for preoperative anaemic adults undergoing nonācardiac surgery [11] demonstrated that patients were much less likely to require red cell transfusion and in those transfused, the volumes were unchanged (mean ...
However, since its introduction to the market in 2013, the drug’s efficacy in cats has been subject to extensive study. The post Apoquel for Cats: Uses, Dosage, & Side Effects appeared first on ...
Epoetin alfa, sold under the brand name Epogen among others, is a human erythropoietin produced in cell culture using recombinant DNA technology. [8] [9] Epoetin alfa is an erythropoiesis-stimulating agent. [8]
The post Penicillin for Cats: Uses, Dosage, & Side Effects appeared first on CatTime. It falls under the beta-lactam class of antibiotics and is primarily used to treat bacterial infections.
A vaccine-associated sarcoma (VAS) or feline injection-site sarcoma (FISS) is a type of malignant tumor found in cats (and, often, dogs and ferrets) which has been linked to certain vaccines. VAS has become a concern for veterinarians and cat owners alike and has resulted in changes in recommended vaccine protocols.
In most parts of the country, shelters recorded notably lower rates of cat surrenders in 2024 than in 2023 and 2022, with around 340,000 cats surrendered to shelters by December of last year ...