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The risk was best seen in cases with underlying silicosis, with relative risks for lung cancer of 2–4. Numerous subsequent studies have been published confirming this risk. In 2006, Pelucchi et al. concluded, "The silicosis-cancer association is now established, in agreement with other studies and meta-analysis." [16]
The risk estimates correspond to a unit risk of approximately 3–6 × 10 −5 per Bq/m 3, assuming a lifetime risk of lung cancer of 3%. This means that a person living in an average European dwelling with 50 Bq/m 3 has a lifetime excess lung cancer risk of 1.5–3 × 10 −3 .
Close family members of those with lung cancer have around twice the risk of developing lung cancer as an average person, even after controlling for occupational exposure and smoking habits. [78] Genome-wide association studies have identified many gene variants associated with lung cancer risk, each of which contributes a small risk increase. [79]
Thousands of smokers and ex-smokers will be invited for free NHS lung cancer screening to help detect the disease early. ... if considered at risk - will be offered a follow-up scan on a mobile ...
According to the NRC, 1 WLM is a 5 to 10 mSv lung dose (0.5 to 1.0 rem), while the Organisation for Economic Co-operation and Development (OECD) consider that 1 WLM is equal to a lung dose of 5.5 mSv, and the International Commission on Radiological Protection (ICRP) consider 1 WLM to be a 5 mSv lung dose for professional workers (and a 4 mSv ...
Environmental diseases are a direct result from the environment. This includes diseases caused by substance abuse, exposure to toxic chemicals, and physical factors in the environment, like UV radiation from the sun, as well as genetic predisposition.
[40] [41] [42] Diesel combustion exhaust is a source of atmospheric soot and fine particles, which is a component of the air pollution implicated in human cancer, [43] [44] heart and lung damage, [45] and mental functioning. [46]
Squamous-cell carcinoma of the lung is closely correlated with a history of tobacco smoking, more so than most other types of lung cancer.According to the Nurses' Health Study, the relative risk of SCC is approximately 5.5, both among those with a previous duration of smoking of 1 to 20 years, and those with 20 to 30 years, compared to never-smokers. [2]
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