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Low platelet count (thrombocytopenia) and low white blood cell count may be due to the disease or a side effect of pharmacological treatment. People with SLE may have an association with antiphospholipid antibody syndrome [ 26 ] (a thrombotic disorder), wherein autoantibodies to phospholipids are present in their serum.
In fact, 90 percent of people diagnosed with the life-long condition are young women between the ages of 15 and 34.
Leukocytosis is a condition in which the white cell count is above the normal range in the blood. [1] [2] It is frequently a sign of an inflammatory response, [3] most commonly the result of infection, but may also occur following certain parasitic infections or bone tumors as well as leukemia.
Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. [1] Symptoms of these diseases can affect many different body systems, including joints, skin, kidneys, blood cells, heart, and lungs. The most common and most severe form is systemic lupus erythematosus.
The Centers for Disease Control and Prevention estimates that more than 200,000 people in the U.S. have lupus, though the Lupus Foundation of America puts the total much higher: roughly 1.5 ...
The clinical signs and symptoms of leukostasis are non-specific but should be suspected in susceptible individuals with leukemia, a high white blood cell count (e.g., over 100,000), and new-onset neurologic or respiratory signs or symptoms. Rales may be heard when listening to the lungs with a stethoscope. [6]
The oral drug, brepocitinib, did not meet the primary study goal of reduction in disease activity at week 52 in patients of SLE, in which the immune system that normally helps protect the body ...
The presentation of the disease varies considerably from one patient to another. [8] Generally, the symptoms include nonspecific symptoms common to connective tissue diseases such as fatigue – this is common in autoimmune diseases, and is the patient's primary concern [9] malaise; fever [10] These can be the initial presentation for some ...
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