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  2. Blinatumomab - Wikipedia

    en.wikipedia.org/wiki/Blinatumomab

    Blinatumomab linking a T cell to a malignant B cell. Blinatumomab is a bispecific T-cell engager (BiTE). [7] It enables a patient's T cells to recognize malignant B cells. A molecule of blinatumomab combines two binding sites: a CD3 site for T cells and a CD19 site for the target B cells. CD3 is part of the T cell receptor.

  3. Amgen (AMGN) Q4 2024 Earnings Call Transcript - AOL

    www.aol.com/finance/amgen-amgn-q4-2024-earnings...

    There are 100 million patients globally in need of effective treatment for lowering their LDL-C. ... who are progressing on or after chemotherapy, is off to a strong start, generating $115 million ...

  4. Brentuximab vedotin - Wikipedia

    en.wikipedia.org/wiki/Brentuximab_vedotin

    Brentuximab vedotin [6] consists of the chimeric monoclonal antibody brentuximab (cAC10, which targets the cell-membrane protein CD30) linked with maleimide attachment groups, cathepsin-cleavable linkers (valine-citrulline), and para-aminobenzylcarbamate spacers to three to five units of the antimitotic agent monomethyl auristatin E (MMAE, reflected by the 'vedotin' in the drug's name). [7]

  5. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    Blinatumomab: Treatment of CD19-positive Philadelphia chromosome-negative B-cell precursor acute lymphoblastic leukemia (ALL) in the consolidation phase of multiphase chemotherapy in people aged one month of age and older [2] Budesonide: For twelve weeks of treatment in people aged eleven years of age and older with eosinophilic esophagitis [2]

  6. RespireRx Pharmaceuticals Inc. CFO and CEO Issue Letter to ...

    lite.aol.com/tech/story/0022/20250210/9355584.htm

    Glen Rock, N.J., Feb. 10, 2025 (GLOBE NEWSWIRE) -- RespireRx Pharmaceuticals Inc. (“RespireRx” or the “Company”), a leader in the discovery and development of innovative and revolutionary treatments to combat diseases caused by disruption of neuronal signaling, today provides a progress and status report to its stockholders, stakeholders, strategic partners as well as other interested ...

  7. Affordable Care Act - Wikipedia

    en.wikipedia.org/wiki/Affordable_Care_Act

    [287] 2.3 million of the approximately 4.6 million people aged 18–64 with undiagnosed diabetes in 2009–2010 may also have gained access to zero-cost preventative care due to section 2713 of the ACA, which prohibits cost sharing for United States Preventive Services Taskforce grade A or B recommended services, such as diabetes screenings. [287]

  8. Ann Wilson announces cancer diagnosis, postpones Heart tour - AOL

    www.aol.com/entertainment/ann-wilson-announces...

    Ann Wilson, lead singer of rock band Heart, says she has cancer and the band is postponing the remaining shows on its Royal Flush Tour while she undergoes treatment. Wilson said in a statement ...

  9. The Terrible—and Amazing—Side Effects of Weight-Loss Drugs

    www.aol.com/terrible-amazing-side-effects-weight...

    GLP-1 drugs used for weight loss involve all kinds of side effects—good and not-so-good—that may or may not strike the average user. (Reminder that there are many of these meds now.