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Variable binding relates three things: a variable v, a location a for that variable in an expression and a non-leaf node n of the form Q(v, P). Note: we define a location in an expression as a leaf node in the syntax tree. Variable binding occurs when that location is below the node n. In the lambda calculus, x is a bound variable in the term M ...
Mechanism of class-switch recombination that allows isotype switching in activated B cells. Immunoglobulin class switching, also known as isotype switching, isotypic commutation or class-switch recombination (CSR), is a biological mechanism that changes a B cell's production of immunoglobulin from one type to another, such as from the isotype IgM to the isotype IgG. [1]
A variable n is bound if it is in the scope of at least n binders (λ); otherwise it is free. The binding site for a variable n is the nth binder it is in the scope of, starting from the innermost binder. The most primitive operation on λ-terms is substitution: replacing free variables in a term with
The term closure is often used as a synonym for anonymous function, though strictly, an anonymous function is a function literal without a name, while a closure is an instance of a function, a value, whose non-local variables have been bound either to values or to storage locations (depending on the language; see the lexical environment section below).
The abstraction operator, λ, is said to bind its variable wherever it occurs in the body of the abstraction. Variables that fall within the scope of an abstraction are said to be bound. In an expression λx.M, the part λx is often called binder, as a hint that the variable x is getting bound by prepending λx to M.
The substitution rule states that for any φ and any term t, one can conclude φ[t/x] from φ provided that no free variable of t becomes bound during the substitution process. (If some free variable of t becomes bound, then to substitute t for x it is first necessary to change the bound variables of φ to differ from the free variables of t.)
Access to variables and methods of an object is given by the private binding object which exists in each ruby class. It is easy to get access to methods and variables within the method of a class. But to access variables of a different class, that class will have to expose its binding object via a public method. The example is as shown below ...
Somatic hypermutation (or SHM) is a cellular mechanism by which the immune system adapts to the new foreign elements that confront it (e.g. microbes).A major component of the process of affinity maturation, SHM diversifies B cell receptors used to recognize foreign elements and allows the immune system to adapt its response to new threats during the lifetime of an organism. [1]