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Giant cell arteritis (GCA), also called temporal arteritis, is an inflammatory autoimmune disease of large blood vessels. [ 4 ] [ 7 ] Symptoms may include headache , pain over the temples, flu-like symptoms , double vision , and difficulty opening the mouth. [ 3 ]
Declining due to improved treatment of strep throat [30] Kawasaki disease: Coronary arteries: Unknown Probable 20 per 100,000 children under age 5 [31] Giant cell arteritis: Large and medium arteries, can affect coronary arteries None specific Confirmed 200 per 100,000 (over age 50) [32] [33] Takayasu's arteritis: Large arteries, including the ...
Arteritis is a vascular disorder characterized by inflammation of the walls of arteries, [1] usually as a result of infection or autoimmune responses. Arteritis, a complex disorder, is still not entirely understood. [2] Arteritis may be distinguished by its different types, based on the organ systems affected by the disease. [2]
GPA treatment depends on the severity of the disease. [8] Severe disease is typically treated with a combination of immunosuppressive medications such as rituximab or cyclophosphamide and high-dose corticosteroids to control the symptoms of the disease , and azathioprine , methotrexate , or rituximab to keep the disease under control.
Giant cell arteritis is most prevalent in older individuals, with the rate of disease being seen to increase from age 50. Women are 2–3 times more likely to develop the disease than men. Northern Europeans have been observed to have a higher incidence of giant cell arteritis compared to southern European, Hispanic, and Asian populations.
An overall feeling of illness or flu-like symptoms. Low-grade (mild) fever [12] or abnormal temperature is sometimes present. High or spiking fevers may occur in patients who also have giant cell arteritis. [2] Generalized weakness Note that this is generalized weakness, not muscle weakness. The presence of muscle weakness likely indicates a ...
The disease's symptoms can range from catastrophic neurological impairment to an asymptomatic condition brought on by impalpable pulses or bruits. [7] Non-specific features include mild anemia, myalgia, arthralgia, weight loss, malaise, night sweats, and fever. [8] Giant cell arteritis (GCA) is the most common type of systemic vasculitis in adults.
AAION is due to temporal arteritis (also called giant-cell arteritis), an inflammatory disease of medium-sized blood vessels (Chapel-Hill-Conference) that occurs especially with advancing age. In contrast, NAION results from the coincidence of cardiovascular risk factors in a patient with "crowded" optic discs.