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Stereocilia (or stereovilli or villi) are non-motile apical cell modifications. They are distinct from cilia and microvilli, but are closely related to microvilli. They form single "finger-like" projections that may be branched, with normal cell membrane characteristics. They contain actin.
In this situation, the hair cells become hyperpolarized and the nerve afferents are not excited. [7] [8] [9] There are two different types of fluid that surround the hair cells of the inner ear. The endolymph is the fluid that surrounds the apical surfaces of hair cells.
Pictures G-N show the tip links connecting the stereocilia. Tip links are extracellular filaments that connect stereocilia to each other or to the kinocilium in the hair cells of the inner ear . [ 1 ] [ 2 ] Mechanotransduction is thought to occur at the site of the tip links, which connect to spring-gated ion channels. [ 3 ]
A kinocilium is a special type of cilium on the apex of hair cells located in the sensory epithelium of the vertebrate inner ear. Contrasting with stereocilia, which are numerous, there is only one kinocilium on each hair cell. The kinocilium can be identified by its apical position as well as its enlarged tip. [1]
The canal which comprises the internal auditory meatus is short (about 1 cm) and runs laterally into the bone. The lateral (outer) aspect of the canal is known as the fundus. [1] The fundus is subdivided by two thin crests of bone to form three separate canals, through which course the facial and vestibulocochlear nerve branches.
Cross-section through the spiral organ of Corti at greater magnification, showing position of the hair cells on the basement membrane. The organ of Corti is located in the scala media of the cochlea of the inner ear between the vestibular duct and the tympanic duct and is composed of mechanosensory cells, known as hair cells. [2]
Dogs have ear mobility that allows them to rapidly pinpoint the exact location of a sound. Eighteen or more muscles can tilt, rotate, raise, or lower a dog's ear. A dog can identify a sound's location much faster than a human can, as well as hear sounds at four times the distance. [41] Dogs can lose their hearing from age or an ear infection. [42]
Studies researching damaged dark cells due to genetic abnormalities or therapeutics are very important in attempting to understand the onset and mechanism of said balance impairments. [9] Dogs have been used as models due to similarities between humans and dogs with regards to inner ear size, inner ear lesions and susceptibility to ototoxins. [9]