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Atopic dermatitis (AD), also known as atopic eczema, is a long-term type of inflammation of the skin. [2] Atopic dermatitis is also often called simply eczema but the same term is also used to refer to dermatitis, the larger group of skin conditions. [2] [5] Atopic dermatitis results in itchy, red, swollen, and cracked skin. [2]
Nemolizumab is indicated for the treatment of adults with prurigo nodularis. [1] [2] In December 2024, the indication for nemolizumab was updated to include the treatment of people twelve years of age and older with moderate-to-severe atopic dermatitis in combination with topical corticosteroids and/or calcineurin inhibitors when the disease is not adequately controlled with topical ...
The SCORAD index was developed by the European Task Force on Atopic Dermatitis in 1993. [3] The index was the most widely used disease-severity scale for atopic dermatitis between its development and 2010. [4]
Atopic dermatitis is a chronic dermatitis associated with a hereditary tendency to develop allergies to food and inhalant substances. [ 46 ] [ 47 ] [ 48 ] Atopic dermatitis (atopic eczema, disseminated neurodermatitis, flexural eczema, infantile eczema, prurigo diathsique)
The term atopic dermatitis was coined in 1933 by Wise and Sulzberger. [95] Sulfur as a topical treatment for eczema was fashionable in the Victorian and Edwardian eras. [84] The word dermatitis is from the Greek δέρμα derma 'skin' and -ῖτις-itis 'inflammation' and eczema is from Greek: ἔκζεμα ekzema 'eruption'. [96]
The allergic march (also called atopic march) is a medical term used to explain the natural history of atopic manifestations. The allergic march is characterized by some antibody responses to immunoglobulin E (IgE) and clinical symptoms that may appear in childhood, and continue for years or decades and often changing with age. [ 1 ]
The Eczema Area and Severity Index (EASI) is a validated tool for the measurement of severity of atopic dermatitis.It ranges from 0 (no disease) to 72 (maximal disease). [1] [2] The EASI was developed in 1998 by modifying the Psoriasis Area and Severity Index (PASI), a widely accepted scoring system for psoriasis.
Any dermatitis may heal leaving pale skin, as may excessive use of corticosteroid creams used to treat episodes of eczema. The hypopigmentation is due to both reduced activity of melanocytes with fewer and smaller melanosomes. [5] [6] The cause of pityriasis alba is not known. Dry skin and atopic dermatitis may co-exist.