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An abnormal increase in basophil granulocytes is therefore also described as basophilia. [2] The opposite of basophilic structures are acidophilic structures, also called eosinophilic. These structures contain many positive charges and are thus strongly stained by anionic dyes like eosin.
Basophilia, as it is primarily a secondary condition, is treated by addressing the causative disease or disorder. The underlying condition will determine what treatment is appropriate. Specifically in cases of allergic reactions or associated with chronic inflammation, treating the underlying cause is critical to avoid further, potentially ...
The white blood cell differential is a common blood test that is often ordered alongside a complete blood count.The test may be performed as part of a routine medical examination; to investigate certain symptoms, particularly those suggestive of infection or hematological disorders; [5] [6] or to monitor existing conditions, such as blood disorders and inflammatory diseases.
Basophilic stippling, also known as punctate basophilia, is the presence of numerous basophilic granules that are dispersed through the cytoplasm of erythrocytes in a peripheral blood smear. They can be demonstrated to be RNA .
Basophilia is also uncommon but may be seen in some forms of leukemia or lymphoma. Clinical significance. Immunophenotyping. Basophils of mice and humans have ...
Differentiated (basophilic granules by light microscopy) and poorly differentiated cases; Majority are poorly differentiated. MPO negative by light microscopy; granules positive in a speckled pattern by electron microscopy.
Necrobiosis is the physiological death of a cell, and can be caused by conditions such as basophilia, erythema, or a tumor. It is identified both with [1] and without necrosis. Necrobiotic disorders are characterized by presence of necrobiotic granuloma on histopathology.
Positive acute-phase proteins serve (as part of the innate immune system) different physiological functions within the immune system.Some act to destroy or inhibit growth of microbes, e.g., C-reactive protein, mannose-binding protein, [3] complement factors, ferritin, ceruloplasmin, serum amyloid A and haptoglobin.