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The Pfizer–BioNTech vaccine must be kept at extremely low temperatures to ensure effectiveness, roughly between −80 and −60 °C (−112 and −76 °F). The vaccine can be stored at 2 to 8 °C (36 to 46 °F) for thirty days before use [157] [158] and at 25 °C (77 °F) [26] [30] or 30 °C (86 °F) [159] [8] for up to two hours before use ...
In March 2021, 19% of US adults claimed to have been vaccinated while 50% announced plans to get vaccinated. [ 150][ 151] A 2022 study found a link between online COVID-19 misinformation and early vaccine hesitancy and refusal. [ 152] Despite a strong association between vaccine hesitancy and Republican vote share at the US county and state ...
Over the course of the COVID-19 pandemic, COVID-19 vaccine mandates have been enacted by numerous states and municipalities in the United States, and also by private entities. In September 2021, President Joe Biden announced that the federal government would take steps to mandate COVID-19 vaccination for certain entities under the authority of ...
The Moderna COVID‑19 vaccine, sold under the brand name Spikevax, is a COVID-19 vaccine developed by the American company Moderna, the United States National Institute of Allergy and Infectious Diseases (NIAID), and the Biomedical Advanced Research and Development Authority (BARDA). Depending on the jurisdiction, it is authorized for use in ...
SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), the virus that causes COVID-19, was isolated in late 2019. [ 1] Its genetic sequence was published on 11 January 2020, triggering an urgent international response to prepare for an outbreak and hasten the development of a preventive COVID-19 vaccine. [ 2][ 3][ 4] Since 2020, vaccine ...
The Sanofi–GSK COVID‑19 vaccine is a recombinant protein subunit vaccine containing the SARS-CoV-2 spike protein, which is produced in insect cells via a baculovirus vector. It also includes an adjuvant made by GSK. It uses the same technology as Sanofi's Flublok influenza vaccine. [ 7][ 8]
The study showed that Phase II trials had a higher immune response and induced T-cell response due to the difference in dosing regime from Phase I. The doses in Phase II were given at 4 weeks interval as opposed to 2 weeks in Phase I. Neutralization response of the vaccine were found significantly higher in Phase II. [31]
The vaccine was the first single-dose vaccine to be authorized in Canada. [64] Delivery times for the vaccine remain unknown. [65] After an agreement was reached with Pfizer to move up some deliveries, it was projected a total of 8 million vaccine doses (from three suppliers) will be available in Canada by the end of March 2021. [66]