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rare. Richter's transformation (RT), also known as Richter's syndrome, is the conversion of chronic lymphocytic leukemia (CLL) or its variant, small lymphocytic lymphoma (SLL), into a new and more aggressively malignant disease. [ 1] CLL is the circulation of malignant B lymphocytes with or without the infiltration of these cells into lymphatic ...
Chronic lymphocytic leukemia. Chronic lymphocytic leukemia ( CLL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell ). [ 2][ 8] Early on, there are typically no symptoms. [ 2] Later, non-painful lymph node swelling, feeling tired, fever, night sweats, or weight loss for no clear reason may occur ...
Hematology, oncology. T-cell-prolymphocytic leukemia (T-PLL) is a mature T-cell leukemia with aggressive behavior and predilection for blood, bone marrow, lymph nodes, liver, spleen, and skin involvement. [1] T-PLL is a very rare leukemia, primarily affecting adults over the age of 30. It represents 2% of all small lymphocytic leukemias in ...
Oncology, hematology. Adult T-cell leukemia/lymphoma ( ATL or ATLL) is a rare cancer of the immune system's T-cells [ 1][ 2][ 3] caused by human T cell leukemia/lymphotropic virus type 1 ( HTLV-1 ). [ 4] All ATL cells contain integrated HTLV-1 provirus further supporting that causal role of the virus in the cause of the neoplasm. [ 4]
T-cell prolymphocytic leukemia (T-PLL) is a very rare and aggressive leukemia affecting adults; somewhat more men than women are diagnosed with this disease. [24] Despite its overall rarity, it is the most common type of mature T cell leukemia; [25] nearly all other leukemias involve B cells. It is difficult to treat, and the median survival is ...
Large granular lymphocytic (LGL) leukemia is a chronic lymphoproliferative disorder that exhibits an unexplained, chronic (> 6 months) elevation in large granular lymphocytes (LGLs) in the peripheral blood. [1] It is divided in two main categories: T-cell LGL leukemia (T-LGLL) and natural-killer (NK)-cell LGL leukemia (NK-LGLL).
T-cell leukemia describes several different types of lymphoid leukemia which affect T cells . Types include: [1] Large granular lymphocytic leukemia. Adult T-cell leukemia/lymphoma. T-cell prolymphocytic leukemia. In practice, it can be hard to distinguish T-cell leukemia from T-cell lymphoma, and they are often grouped together.
By Mariam Sunny. (Reuters) -The U.S. Food and Drug Administration said on Friday it has approved Adaptimmune's first-of-its-kind treatment for a rare type of cancer in the soft tissues that most ...
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