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Levacetylleucine. Levacetylleucine, sold under the brand name Aqneursa, is a medication used for the treatment of neurological manifestations of Niemann-Pick disease type C. [1][2] Levacetylleucine is a modified version of the amino acid leucine (N-Acetyl-L-Leucine). [1] It is taken by mouth.
Leucine (symbol Leu or L) [3] is an essential amino acid that is used in the biosynthesis of proteins.Leucine is an α-amino acid, meaning it contains an α-amino group (which is in the protonated −NH 3 + form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO − form under biological conditions), and a side chain isobutyl group, making it a non ...
Drugs in pregnancy. Women should speak to their doctor or healthcare professional before starting or stopping any medications while pregnant. [1] Drugs taken in pregnancy including over-the counter-medications, prescription medications, nutritional supplements, recreational drugs, and illicit drugs may cause harm to the mother or the unborn child.
[22] [23] Levacetylleucine is a modified version of the amino acid leucine (N-Acetyl-L-Leucine). [22] It is taken by mouth. [22] The most common side effects include abdominal pain, difficulty swallowing, upper respiratory tract infections, and vomiting. [22] [23] Levacetylleucine was approved for medical use in the United States in September 2024.
The United States Preventive Services Task Force recommends a low-dose regimen for women at high risk beginning in the 12th week. [71] Benefits are less if started after 16 weeks. [72] Since 2018 the American College of Obstetricians and Gynecologists has recommended low-dose aspirin therapy as standard preventive treatment for pre-eclampsia. [73]
Gestational diabetes is a condition in which a woman without diabetes develops high blood sugar levels during pregnancy. [2] Gestational diabetes generally results in few symptoms; [2] however, obesity increases the rate of pre-eclampsia, cesarean sections, and embryo macrosomia, as well as gestational diabetes. [2]
[13] [29] Serious side effects may include angioedema, drug misuse, and an increased suicide risk. [13] When pregabalin is taken at high doses over a long period of time, addiction may occur, but if taken at usual doses the risk is low. [4] Use during pregnancy or breastfeeding is of unclear safety. [30]
Leuprorelin. Leuprorelin, also known as leuprolide, is a manufactured version of a hormone used to treat prostate cancer, breast cancer, endometriosis, uterine fibroids, for early puberty, or as part of transgender hormone therapy. [10][11] It is given by injection into a muscle or under the skin. [10]
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