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Congenital vertebral anomalies are a collection of malformations of the spine. Most, around 85%, are not clinically significant, but they can cause compression of the spinal cord by deforming the vertebral canal or causing instability. This condition occurs in the womb.
The segmentation pattern observed in the spinal nerves is in fact governed by the somatic mesoderm. In the embryonic stages of higher vertebrates including humans, the segmentation of these spinal nerves follows the directions from both the anterior (A, cranial) and posterior (P, caudal) sections of the somite mesoderm.
The three categories treated for types of spinal cord deficiencies are massive fusion of the cervical spine (Type I), the fusion of 1 or 2 vertebrae (Type II), and the presence of thoracic and lumbar spine anomalies in association with type I or type II Klippel–Feil syndrome (Type III). [citation needed]
The filum terminale is situated centrally [2] amid the spinal nerve roots of the cauda equina [3] [2] (but is not itself a part of the cauda equina [2]).. The inferior-most spinal nerve, the coccygeal nerve, leaves the spinal cord at the level of the conus medullaris via respective vertebrae through their intervertebral foramina, superior to the filum terminale.
The spinal cord and its nerve roots are put back inside the spine and covered with meninges. In addition, a shunt may be surgically installed to provide a continuous drain for the excess cerebrospinal fluid produced in the brain, as happens with hydrocephalus. Shunts most commonly drain into the abdomen or chest wall. [citation needed]
In addition, the somites specify the migration paths of neural crest cells and the axons of spinal nerves. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body.
It is a congenital disorder in which the fetal development of the lower spine—the caudal partition of the spine—is abnormal. [1] It occurs at a rate of approximately one per 60,000 live births. [2] Some babies are born with very small differences compared to typical development, and others have significant changes.
In human anatomy, arcuate foramen, also known as ponticulus posticus (Latin for "little posterior bridge") or Kimmerle's anomaly, [1] refers to a bony bridge on the atlas (C1 vertebra) that covers the groove for the vertebral artery. It is a common anatomical variation and estimated to occur in approximately 3-15% of the population.