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2. Sildenafil - Wikipedia

   en.wikipedia.org/wiki/Sildenafil

   Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [ 4 ] [ 8 ] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon . [ 9 ]

3. Viagra: What It Treats & Its Side Effects ( Plus What It Was ...

   www.aol.com/viagra-treats-side-effects-plus...

   Sildenafil could also cause an increased risk of heart attack or other heart problems. If you have an irregular heartbeat, hearing loss, vision loss, an allergic reaction, Peyronie’s disease, or ...

4. What Does Viagra Actually Do to Your "Intimate" Experience? - AOL

   www.aol.com/does-viagra-actually-intimate...

   The mechanism of action of other ... What Does Viagra Do? Viagra works by improving blood flow to your privates. The active ingredient, Sildenafil, is a PDE5 inhibitor that helps blood vessels ...

5. PDE5 inhibitor - Wikipedia

   en.wikipedia.org/wiki/PDE5_inhibitor

   Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

6. 5 Must-Know Tips Before Taking Sildenafil 100mg - AOL

   www.aol.com/5-must-know-tips-taking-105700758.html

   Sildenafil and other PDE-5 inhibitor medications can interact with other drugs, including several common medications used to treat chest pain, high blood pressure (sildenafil can cause low blood ...

7. Discovery and development of phosphodiesterase 5 inhibitors

   en.wikipedia.org/wiki/Discovery_and_development...

   The major PDE5 inhibitors (a subset of the phosphodiesterase inhibitors) are sildenafil, tadalafil, vardenafil, and avanafil, and although all share the same mechanism of action each has unique pharmacokinetic and pharmacodynamic properties which dictate their suitability in various conditions and their side effect profile. [3]

8. How to Take Viagra for Best Results - AOL

   www.aol.com/viagra-best-results-105700318.html

   Like other prescription medicines, Viagra and its generic form, sildenafil, work best when you take them under the right conditions. Like other prescription medicines, Viagra and its generic form ...

9. Mechanism of action - Wikipedia

   en.wikipedia.org/wiki/Mechanism_of_action

   In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect. [2] A mechanism of action usually includes mention of the specific molecular targets to which the drug binds, such as an enzyme or receptor . [ 3 ]