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Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, migraines, or surgery. [8] It is also effective for treating gastroenteritis .
Adverse effects include a transient increase in serum glucose level, and poor wound healing (controversial). Medications include dexamethasone. Butyrophenones are typically administered as a single injection at the end of surgery. Adverse effects include prolongation of the QT interval on EKG. Medications include droperidol and haloperidol.
Side effects in dogs and cats include hypersalivation, diarrhea, loss of appetite, and vomiting. [12] [16] Eight percent of dogs taking maropitant at doses meant to prevent motion sickness vomited right after, likely due to the local effects maropitant had on the gastrointestinal tract. Small amounts of food beforehand can prevent such post ...
Related: Benadryl for Dogs: Side Effects of Long-Term Use Signs of Benadryl Overdose in Dogs At normal doses, Benadryl is quite safe, but a survey of over 600 dogs (1) found the following signs of ...
Ondansetron was approved by the U.S. Food and Drug Administration in 1991, and has since become available in several other countries, including the UK, Ireland, Australia, Canada, France and Brazil. As of 2008, ondansetron and granisetron are the only 5-HT 3 antagonists available as a generic drug in the United States. Ondansetron may be given ...
It is most common in dogs six to eight months old. Surgery is necessary for treatment. [149] Lymphangiectasia is an intestinal disease of dogs characterized by chronic diarrhea and loss of proteins such as serum albumin and globulin. It is considered to be a chronic form of protein-losing enteropathy.
Ondansetron; Palonosetron; Tropisetron; Other 5-HT 3 antagonists have been considered for use in the treatment of irritable bowel syndrome: Alosetron; Cilansetron; Also, the antidepressant mirtazapine acts as a 5-HT 3 antagonist.
The lethal dose for 50% of dogs is 100 – 200 mg per kilogram (kg) of body weight, yet some dogs will exhibit signs of toxicosis after ingesting as little as 20 mg per kg. [38] In case of accidental intake of chocolate, especially involving a smaller dog, contact a veterinarian or animal poison control immediately; it is commonly recommended ...