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At higher doses, niacin has been used to treat high cholesterol and triglyceride levels, since it can help lower LDL (“bad”) cholesterol and raise levels of HDL (“good”) cholesterol.
Acipimox (trade name Olbetam in Europe) is a niacin derivative used as a lipid-lowering agent.It reduces triglyceride levels and increases HDL cholesterol. It may have less marked adverse effects than niacin, although it is unclear whether the recommended dose is as effective as standard doses of niacin.
Laropiprant is a prostaglandin D2 binding drug shown to reduce niacin-induced vasodilation and flushing side effects. [30] [77] [78] A clinical trial showed no additional efficacy of Tredaptive in lowering cholesterol when used together with other statin drugs, but did show an increase in other side effects. [79]
Medical practitioners prescribe recommended doses up to 2000 mg per day of niacin in either immediate-release or slow-release formats, to lower plasma triglycerides and low-density lipiprotein cholesterol. [25] Vitamin B 5: None: No toxicity known. Vitamin B 6: US UL = 100 mg/day; EU UL = 25 mg/day: See Megavitamin-B 6 syndrome for more ...
The phenolic compounds and saponins in quinoa may help reduce the risk of cardiovascular disease and diabetes, and its soluble fiber helps decrease triglycerides and LDL levels in the body while ...
Many lifestyle changes can help lower cholesterol. Even so, sometimes you might need to take medications as well. 10 Ways to Naturally Lower Cholesterol, According to Doctors
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