Search results
Results from the WOW.Com Content Network
[1] [2] [3] It is also the N,N-dimethylated derivative of 5-methoxy-α-methyltryptamine (5-MeO-αMT or α,O-DMS) and the N-methylated derivative of 5-methoxy-α,N-dimethyltryptamine (5-MeO-α,N-DMT or α,N,O-TMS). [1] [2] [3] The compound was described by Alexander Shulgin in TiHKAL as a putative psychedelic drug, but does not appear to have ...
5-Methoxy-7,N,N-trimethyltryptamine (5-MeO-7,N,N-TMT, 5-MeO-7-TMT), is a tryptamine derivative which acts as a partial agonist at the 5-HT 2 serotonin receptors, with an EC 50 of 63.9 nM and an efficacy of 66.2% at 5-HT 2A (vs 5-HT), and weaker activity at 5-HT 2B and 5-HT 2C. [1] [2] [3] In animal tests, both 7,N,N-TMT and 5-MeO-7,N,N-TMT ...
7,N,N-trimethyltryptamine (7-methyl-DMT, 7-TMT), is a tryptamine derivative which acts as an agonist of 5-HT 2 receptors. [1] [2] [3] In animal tests, both 7-TMT and its 5-methoxy derivative 5-MeO-7-TMT produced behavioural responses similar to those of psychedelic drugs such as DMT, but the larger 7-ethyl and 7-bromo derivatives of DMT did not produce psychedelic responses despite having ...
5-Methoxytryptamine (5-MT, 5-MeO-T, or 5-OMe-T), also known as serotonin methyl ether or O-methylserotonin and as mexamine, is a tryptamine derivative closely related to the neurotransmitters serotonin and melatonin. [3]
5-Methyltryptamine (5-MeT, 5-Me-T) is a non-selective serotonin receptor agonist and serotonin releasing agent of the tryptamine family that has been used in scientific research. [ 1 ] [ 2 ] It is related to other 5- substituted tryptamines such as serotonin (5-hydroxytryptamine; 5-HT) and 5-methoxytryptamine (5-MeO-T).
5-MeO-DMT is lipophilic and is thought to easily cross the blood–brain barrier. [2] Accordingly, 5-MeO-DMT readily accumulates in the brain in animals with levels higher than in blood. [2] This is in notable contrast to bufotenin (5-HO-DMT or N,N-dimethylserotonin) and serotonin (5-HT), which are hydrophilic and peripherally selective. [2 ...
α-Methylmelatonin, also known as α-methyl-5-methoxy-N-acetyltryptamine, is a synthetic tryptamine derivative and analogue of the monoamine neurotransmitter melatonin. [1] It is a metabolite of α-methyltryptophan, α-methyl-5-hydroxytryptophan, and α-methylserotonin that can be formed in small amounts via aralkylamine N-acetyltransferase (AANAT).
4-Hydroxy-5-methoxytryptamine (4-HO-5-MeO-T) is a serotonergic neurotoxin of the tryptamine family. [ 1 ] [ 2 ] It is structurally related to the monoamine neurotransmitter serotonin (5-hydroxytryptamine; 5-HT).