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Chlormadinone acetate (CMA), sold under the brand names Belara, Gynorelle, Lutéran, and Prostal among others, is a progestin and antiandrogen medication which is used in birth control pills to prevent pregnancy, as a component of menopausal hormone therapy, in the treatment of gynecological disorders, and in the treatment of androgen-dependent conditions like enlarged prostate and prostate ...
Chlormadinone acetate = 17α-acetoxy-6-chloro-δ 6-progesterone Clometerone (L-38000) = 6α-chloro-16α-methylprogesterone Cyproterone (SH-80881) = 1,2α-methylene-6-chloro-δ 6 -17α-hydroxyprogesterone
Cyproterone acetate (CPA), sold alone under the brand name Androcur or with ethinylestradiol under the brand names Diane or Diane-35 among others, is an antiandrogen and progestin medication used in the treatment of androgen-dependent conditions such as acne, excessive body hair growth, early puberty, and prostate cancer, as a component of feminizing hormone therapy for transgender individuals ...
Medroxyprogesterone acetate (Amen, Curretab, Cycrin, Provera) – 2.5 mg, 5 mg, 10 mg Megestrol acetate (Megace) – 20 mg, 40 mg – approved specifically for the treatment of breast and endometrial cancer [ 46 ] and for the treatment of anorexia , cachexia , and weight loss in patients with AIDS Tooltip acquired immunodeficiency syndrome [ 47 ]
All contain an estrogen, ethinylestradiol or mestranol, [1] [2] in varying amounts, and one of a number of different progestogens. (Regarding the estrogen, the inactive 3-methyl ether of ethinylestradiol, which must be metabolized by the liver into the active ethinylestradiol; 50 μg of mestranol is equivalent to only 35 μg of ethinylestradiol and should not be used when high-dose [50 μg ...
Testosterone levels with 100 to 300 mg/day oral cyproterone acetate and low-dose oral estrogen in men. [160] The estrogen used was 0.1 mg/day diethylstilbestrol (DES), [160] which has been described as an "extremely low" dosage. [87] Levels of testosterone were decreased by about 95% with the combination and by about 61% with cyproterone ...
[1] [2] An acylated derivative, chlormadinone acetate, is used clinically as a pharmaceutical drug. [1] [2] It was patented in 1958 and approved for medical use in 1963. [3] While chlormadinone is sometimes used as a synonym for chlormadinone acetate, what is almost always being referred to is chlormadinone acetate and not chlormadinone.
Cyproterone was studied as a treatment for precocious puberty by Bierich (1970, 1971), but no significant improvement was observed. [22] In men, 100 mg/day cyproterone proved to be rather ineffective in treating acne, which was hypothesized to be related to its progonadotropic effects in males and counteraction of its antiandrogen activity.