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Pharmaceutical grade ethanol is usually given intravenously as a 5 or 10% solution in 5% dextrose, but it is also sometimes given orally in the form of a strong spirit such as whisky, vodka, or gin. [7] Fomepizole is a potent inhibitor of alcohol dehydrogenase; similar to ethanol, it acts to block the formation of the toxic metabolites.
The electronic common technical document (eCTD) is an interface and international specification for the pharmaceutical industry to agency transfer of regulatory information. The specification is based on the Common Technical Document (CTD) format and was developed by the International Council for Harmonisation (ICH) Multidisciplinary Group 2 ...
An International Nonproprietary Name (INN) is an official generic and nonproprietary name given to a pharmaceutical substance or an active ingredient, [1] encompassing compounds, peptides and low-molecular-weight proteins (e.g., insulin, hormones, cytokines), as well as complex biological products, such as those used for gene therapy. [2]
Ethylene glycol (IUPAC name: ethane-1,2-diol) is an organic compound (a vicinal diol [7]) with the formula (CH 2 OH) 2.It is mainly used for two purposes: as a raw material in the manufacture of polyester fibers and for antifreeze formulations.
The FCC has been published since 1966. Before 1960s, although the federal Food and Drug Administration (FDA) had by regulations and informal statements defined in general terms quality requirements for food chemicals generally recognized as safe (), these requirements were not published in the official regulations or designed to be sufficiently specific, therefore their use for general ...
Poloxamers are also known by the trade names Pluronic, [2] Kolliphor (pharma grade), [3] and Synperonic. [ 4 ] Because the lengths of the polymer blocks can be customized, many different poloxamers exist that have slightly different properties.
The reaction from ethanol to carbon dioxide and water proceeds in at least 11 steps in humans. C 2 H 6 O (ethanol) is converted to C 2 H 4 O (acetaldehyde), then to C 2 H 4 O 2 (acetic acid), then to acetyl-CoA. Once acetyl-CoA is formed, it is free to enter directly into the citric acid cycle (TCA) and is converted to 2 CO 2 molecules in 8 ...
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