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Levels of DHEA-S in circulation are approximately 250 to 300 times those of DHEA. [20] DHEA-S in turn can be converted back into DHEA in peripheral tissues via steroid sulfatase (STS). [54] [55] The terminal half-life of DHEA is short at only 15 to 30 minutes. [56] In contrast, the terminal half-life of DHEA-S is far longer, at 7 to 10 hours. [56]
Find out if DHEA can help with a range of health issues, what the side effects are and what alternatives to consider. 5 Uses for DHEA Supplements for Men, From Depression to Testosterone Skip to ...
Prasterone, also known as dehydroepiandrosterone (DHEA) and sold under the brand name Intrarosa among others, is a medication as well as over-the-counter dietary supplement which is used to correct DHEA deficiency due to adrenal insufficiency or old age, as a component of menopausal hormone therapy, to treat painful sexual intercourse due to vaginal atrophy, and to prepare the cervix for ...
Testosterone is the primary male sex hormone and androgen in males. [3] In humans, testosterone plays a key role in the development of male reproductive tissues such as testicles and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair.
1-Androsterone (also known as 1-andro, 1-dehydroepiandrosterone, 1-DHEA, δ 1-epiandrosterone, or 5α-androst-1-en-3β-ol-17-one) is a synthetic, orally active anabolic-androgenic steroid (AAS). [1] It is an androgen prohormone of 1-testosterone (dihydroboldenone), 1-androstenedione , and other 1- dehydrogenated androstanes . [ 1 ]
Side effects of testosterone cypionate include virilization among others. [4] Diminished sperm production is a common side-effect of testosterone replacement therapy because of the decreased intra-testicular concentration of testosterone and suppression of the hypothalamic-pituitary-gonadal axis. [20]
7-Keto-DHEA is not directly converted to testosterone or estrogen by the human body. [3] Due to this fact, the suppliers of supplements have investigated it as a potentially more useful relative of the DHEA steroid when used as a supplementation, but the results are inconclusive.
Common side effects of testosterone include acne, swelling, and breast enlargement in men. [9] Serious side effects may include liver toxicity, heart disease, and behavioral changes. [9] Women and children who are exposed may develop masculinization. [9] It is recommended that individuals with prostate cancer should not use the medication. [9]
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