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Arginine alpha-ketoglutarate (AAKG) is a salt of the amino acid arginine and alpha-ketoglutaric acid. It is marketed as a bodybuilding supplement. [1] Peer-reviewed studies have found no increase in muscle protein synthesis or improvement in muscle strength from use of AAKG as a dietary supplement. [1] [2] [3]
[1] [2] [3] It is a powdered nutritional supplement that contains 3 grams of calcium β-hydroxy β-methylbutyrate, 14 grams of L-arginine, and 14 grams of L-glutamine per two daily servings. [1] Juven has been shown to increase lean body mass during clinical trials in individuals with AIDS and cancer, but not rheumatoid cachexia.
Arginine is the amino acid with the formula (H 2 N)(HN)CN(H)(CH 2) 3 CH(NH 2)CO 2 H. The molecule features a guanidino group appended to a standard amino acid framework. At physiological pH, the carboxylic acid is deprotonated (−CO 2 −) and both the amino and guanidino groups are protonated, resulting in a cation.
l-Arginine l-pyroglutamate, also known as pirglutargine and arginine pidolate, is the l-arginine salt of pyroglutamic acid. Arginine pyroglutamate is a delivery form of arginine. Physical and chemical properties
Protein shakes, made from protein powder (center) and milk (left), are a common bodybuilding supplement. Bodybuilders may supplement their diets with protein for reasons of convenience, lower cost (relative to meat and fish products), ease of preparation, and to avoid the concurrent consumption of carbohydrates and fats. Additionally, some ...
l-Arginine ethyl ester is a white powder quickly soluble in hot water. It has a characteristically bad and bitter taste, thus before drinking it is recommended to mix the powder with a strongly flavored beverage or citrus juice. [dubious – discuss] Arginine ethyl ester falls under the category of protected aminoacids.
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