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Rosuvastatin has multiple contraindications, including hypersensitivity to rosuvastatin or any component of the formulation, active liver disease, elevation of serum transaminases, pregnancy, or breastfeeding. [4] Rosuvastatin is not prescribed nor used while pregnant, as it can cause serious harm to the fetus. [4]
Cerivastatin is the most potent (withdrawn from the market in August 2001 due to risk of serious rhabdomyolysis), followed by (in order of decreasing potency) rosuvastatin, atorvastatin, simvastatin, lovastatin, pravastatin, and fluvastatin. [175]
Type 2 statins have unique fluorophenyl group that causes additional polar interaction between the enzyme and the statins, which results in a tighter binding to the enzyme. The newest statin, rosuvastatin has a unique polar methane sulfonamide group, which is quite hydrophilic and confers low lipophilicity. The sulfonamide group forms a unique ...
Examples of this drug class are atorvastatin, rosuvastatin, fluvastatin, simvastatin, pravastatin and lovastatin. ... Although warfarin is commonly prescribed, ...
[6] [9] In 2022, it was the most commonly prescribed medication in the United States, with more than 109 million prescriptions filled for over 27 million people. [ 10 ] [ 11 ] In Australia, it was one of the top ten most prescribed medications between 2017 and 2023.
Today's NYT Connections puzzle for Wednesday, February 19, 2025The New York Times
The medication isn’t prescribed for type 1 diabetes. The best time to take metformin depends on the medication type and dosage. Some people take metformin once, twice or even three times a day ...
Drugs or medicines may be withdrawn from commercial markets because of risks to patients, but also because of commercial reasons (e.g. lack of demand and relatively high production costs).