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Bleeding problems or stomach ulcers. Liver and kidney problems, including being on dialysis. How to Use Sildenafil Safely. When you’re dealing with ED, it can understandably trigger a range of ...
Likewise, Viagra shouldn’t be combined with antiretroviral drugs used to treat HIV/AIDS, as it can cause an increased concentration of sildenafil in the body. Breastfeeding women shouldn’t ...
Blood vessel and heart disease. Atherosclerosis. Neurological diseases like multiple sclerosis. Peyronie’s disease. Chronic kidney disease. Injury to the penis, spinal cord, prostate, bladder or ...
Kidney disease: ED and chronic kidney disease have pathological mechanisms in common, including vascular and hormonal dysfunction, and may share other comorbidities, such as hypertension and diabetes mellitus that can contribute to ED [9] Lifestyle habits, particularly smoking, which is a key risk factor for ED as it promotes arterial narrowing.
Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9]
Diseases are also common causes of erectile dysfunction. Diseases such as cardiovascular disease, multiple sclerosis, kidney failure, vascular disease, and spinal cord injury can cause erectile dysfunction. [10] Cardiovascular disease can decrease blood flow to penile tissues, making it difficult to develop or maintain an erection.
Using medications when anxious can lead to psychological dependency — a crutch in place of working on the most important problems ( self-confidence, physical health, etc.). Then there’s the ...
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.