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Metabolomics is a peer-reviewed scientific journal covering topics including whole metabolome analysis of organisms, metabolite target analysis, with applications within animals, plants and microbes, pharmacometabolomics for precision medicine, as well as systems biology.
Metabolic engineering is the practice of optimizing genetic and regulatory processes within cells to increase the cell's production of a certain substance. These processes are chemical networks that use a series of biochemical reactions and enzymes that allow cells to convert raw materials into molecules necessary for the cell's survival.
Metabolic Engineering is a peer-reviewed scientific journal covering research on production of fuels and chemicals using microorganisms and other biological systems. The journal specialises in quantitative analyses of metabolic pathways and their relationship to cell physiology in industrial and medical contexts.
Metabolomics is the scientific study of chemical processes involving metabolites, the small molecule substrates, intermediates, and products of cell metabolism. Specifically, metabolomics is the "systematic study of the unique chemical fingerprints that specific cellular processes leave behind", the study of their small-molecule metabolite ...
Multi-omics studies allow for functional analysis of microbiota. [19] Animal models can be used to take more accurate samples of the in situ microbiome. Germ-free animals are used to implant a specific microbiome from another organism to yield a gnotobiotic model. These can be studied to see how it changes under different environmental ...
The first book on metabolomics was published in 2003. [5] The first journal dedicated to metabolomics (titled simply "Metabolomics") was launched in 2005 and is currently edited by Prof. Roy Goodacre. Some of the more significant early papers on metabolome analysis are listed in the references below. [6] [7] [8] [9]
Metabolite Set Enrichment Analysis (MSEA) is a method designed to help metabolomics researchers identify and interpret patterns of metabolite concentration changes in a biologically meaningful way. [1] It is conceptually similar to another widely used tool developed for transcriptomics called Gene Set Enrichment Analysis or GSEA. [2]
Metabolic flux analysis (MFA) is an experimental fluxomics technique used to examine production and consumption rates of metabolites in a biological system. At an intracellular level, it allows for the quantification of metabolic fluxes, thereby elucidating the central metabolism of the cell. [1]