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Clopidogrel, sold under the brand name Plavix among others, is an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. [10] It is also used together with aspirin in heart attacks and following the placement of a coronary artery stent (dual antiplatelet therapy). [10] It is taken by mouth. [10]
Prasugrel is a member of the thienopyridine class of ADP receptor inhibitors, like ticlopidine (trade name Ticlid) and clopidogrel (trade name Plavix). These agents reduce the aggregation ("clumping") of platelets by irreversibly binding to P2Y 12 receptors. Prasugrel inhibits platelet aggregation more rapidly, more consistently, and to a ...
In the US, ticagrelor is indicated to reduce the risk of stroke in people with acute ischemic stroke or high-risk transient ischemic attack. [5]In the EU, ticagrelor, co-administered with acetylsalicylic acid (aspirin), is indicated for the prevention of atherothrombotic events in adults with acute coronary syndromes or a history of myocardial infarction and a high risk of developing an ...
Side effects may include bleeding, most commonly from the nose, gastrointestinal tract (GI) or genitourinary system. [2] Compared to the risk of bleeding with warfarin use, direct factor Xa inhibitors have a higher risk of GI bleeding, but lower risk of bleeding in the brain. [2]
Jeremy Charles Robert Clarkson (born 11 April 1960) is an English television presenter, journalist, farmer, and author who specialises in motoring.He is best known for hosting the television programmes Top Gear (2002–2015) and The Grand Tour (2016–2024) alongside Richard Hammond and James May.
Minuteman III launch from Vandenberg Space Force Base in California on 9 February 2023.. The LGM-30 Minuteman is an American land-based intercontinental ballistic missile (ICBM) in service with the Air Force Global Strike Command.
Blackstone would have put the probability standard for proof "beyond a reasonable doubt" at somewhat more than 90%, for he declared: "It is better that ten guilty persons escape than one innocent suffer." Pi et al. advocate formalizing this in jury instructions. [24]
Star Wars opened to positive reviews, with praise for its special effects. It grossed $410 million worldwide during its initial run, surpassing Jaws (1975) to become the highest-grossing film until the release of E.T. the Extra-Terrestrial (1982); subsequent releases have brought its total gross to $775 million.
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