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After seroconversion, sufficient concentration of the specific antibody exists in the blood, and the serological assay will detect the antibody. The individual is now seropositive for the antibody. [14] During seroconversion, when the amounts of antibody and antigen are very similar, it may not be possible to detect free antigen or free ...
The presence of detectable levels of a specific marker within the serum is considered seropositivity, while the absence of such levels is considered seronegativity. HIV/AIDS [ edit ]
Two serotypes 1a and 1b with antigens 2a and 2b on surface, which are recognized by two distinct antibodies, 3a and 3b, respectively. A serotype or serovar is a distinct variation within a species of bacteria or virus or among immune cells of different individuals.
Serology is the scientific study of serum and other body fluids.In practice, the term usually refers to the diagnostic identification of antibodies in the serum. [1] Such antibodies are typically formed in response to an infection (against a given microorganism), [2] against other foreign proteins (in response, for example, to a mismatched blood transfusion), or to one's own proteins (in ...
A viral titer is the lowest concentration of a virus that still infects cells. To determine the titer, several dilutions are prepared, such as 10 −1, 10 −2, 10 −3, ... 10 −8. [1] The titer of a fat is the temperature, in degrees Celsius, at which it solidifies. [4] The higher the titer, the harder the fat.
Clinically, measured IgG antibody levels are generally considered to be indicative of an individual's immune status to particular pathogens. A common example of this practice are titers drawn to demonstrate serologic immunity to measles, mumps, and rubella (MMR), hepatitis B virus , and varicella (chickenpox), among others.
Correlates of immunity or correlates of protection to a virus or other infectious pathogen are measurable signs that a person (or other potential host) is immune, in the sense of being protected against becoming infected and/or developing disease.
It defines seroconversion and starts the conversation about the response to antigen and antibody formation. It also touches on the importance of the tests used to detect antibodies. Overall, the only critique I have is that it is written at a high-grade level with complex sentences and vocabulary.