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Albumin-bound paclitaxel (brand name Abraxane, also called nab-paclitaxel) is an alternative formulation where paclitaxel is bound to albumin nanoparticles. Much of the clinical toxicity of paclitaxel is associated with the solvent Cremophor EL in which it is dissolved for delivery.
The Texas State Historical Association (TSHA) is an American nonprofit educational and research organization dedicated to documenting the history of Texas. It was founded in Austin, Texas, United States, on March 2, 1897. In November 2008, the TSHA moved its offices from Austin to the University of North Texas in Denton, Texas.
Paclitaxel total synthesis in organic chemistry is a major ongoing research effort in the total synthesis of paclitaxel (Taxol). [1] This diterpenoid is an important drug in the treatment of cancer but, also expensive because the compound is harvested from a scarce resource, namely the Pacific yew ( Taxus brevifolia ).
DHA-paclitaxel (or Taxoprexin) is an investigational drug (from Protarga Inc) made by linking paclitaxel to docosahexaenoic acid (DHA), a fatty acid that is easily taken up by tumor cells; the DHA-paclitaxel “appears not to be cytotoxic until the bond with DHA is cleaved within the cell.” [1] The advantage of DHA-paclitaxel over paclitaxel is DHA-paclitaxel's ability to carry much higher ...
As early as 1836, Americans had debated admitting Texas to the Union as a slave state. "They were concerned Texas would upset the Congressional balance of power between the states," reads one wall ...
The Handbook of Texas. Texas State Historical Association. ISBN 9780876110270. Francaviglia, Richard V. (1998). From sail to steam: four centuries of Texas maritime history, 1500-1900. University of Texas Press. ISBN 978-0-292-72503-4. Allen Ranch from the Handbook of Texas Online; ALLEN, SAMUEL EZEKIEL from the Handbook of Texas Online
(Credit: University of North Texas / Portal to Texas History) Civil rights victory 70 years ago In 2024, the landmark Brown vs. Board of Education case is likely to be in the forefront of civil ...
The Texas Historical Commission is an agency dedicated to historic preservation within the U.S. state of Texas. It administers the National Register of Historic Places for sites in Texas . The commission also identifies Recorded Texas Historic Landmarks (RTHL) and recognizes them with Official Texas Historical Marker (OTHM) medallions and ...