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Albumin-bound paclitaxel (brand name Abraxane, also called nab-paclitaxel) is an alternative formulation where paclitaxel is bound to albumin nanoparticles. Much of the clinical toxicity of paclitaxel is associated with the solvent Cremophor EL in which it is dissolved for delivery.
Paclitaxel total synthesis in organic chemistry is a major ongoing research effort in the total synthesis of paclitaxel (Taxol). [1] This diterpenoid is an important drug in the treatment of cancer but, also expensive because the compound is harvested from a scarce resource, namely the Pacific yew ( Taxus brevifolia ).
Taxoids are a class of derivatives from taxol, [1] that is, paclitaxel.They were developed for their anticancer chemotherapeutic properties. Taxoids are usually treated as synonymous with taxanes; for example, a major medical dictionary defines the two terms with the same definition phrasing, [2] and in another the phrasing varies slightly but conveys nearly identical meaning.
DHA-paclitaxel (or Taxoprexin) is an investigational drug (from Protarga Inc) made by linking paclitaxel to docosahexaenoic acid (DHA), a fatty acid that is easily taken up by tumor cells; the DHA-paclitaxel “appears not to be cytotoxic until the bond with DHA is cleaved within the cell.” [1] The advantage of DHA-paclitaxel over paclitaxel is DHA-paclitaxel's ability to carry much higher ...
In addition, the Handbook of Texas Online is provided by the TSHA for historical internet research of Texas. The Southwestern Historical Quarterly (initially the Quarterly of the Texas State Historical Association) is the oldest continuously published scholarly journal in Texas. The journal features 16 articles per year, covering topics in a ...
Texas historical marker for Jane Long located at Fort Travis Seashore Park, Bolivar Point. Jane Herbert Wilkinson Long (July 23, 1798 – December 30, 1880) was a Texas pioneer. She owned boarding houses and a plantation in Texas. She is best known as the "Mother of Texas."
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The Texas Youth Commission (TYC) was a Texas state agency which operated juvenile corrections facilities in the state. The commission was headquartered in the Brown-Heatly Building in Austin . As of 2007, it was the second largest juvenile corrections agency in the United States, after the Florida Department of Juvenile Justice . [ 1 ]