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Side effects from intra-articular administration can include joint pain, swelling, lameness, and, rarely, infection of the joint. Intramuscular injection can cause dose-dependent inflammation and bleeding, since PSGAG is an analogue of the anticoagulant heparin. [4] In dogs, this may manifest as bleeding from the nose or as bloody stools. [7]
The degree of these effects in horses after intramuscular injection has relatively little support in the current literature. [35] However, there is much anecdotal evidence of their benefits for synovitis and osteoarthritis, and PSGAGs are very commonly used by veterinarians in the United States involved in racehorse and show horse practice. [36]
In horses, prednisolone acetate suspensions are priorly used to treat inflammation in the middle layer of the eye, also known as anterior uveitis and equine recurrent uveitis (ERU), which is the leading cause of visual impairment in horses. [58] Prednisolone acetate eye drops are not to be used in other animals such as birds. [57]
Horse ointment, known as horse oil and horse fat, is a topical formulation derived from subcutaneous fat of horses. [1] Due to its thickness and viscosity , horse ointment is intended for topical use on human skin and mucous membranes to moisturize and increase the restoration of damaged skin.
Side effects are not common, but the use of acepromazine in stallions should be used with caution (but is not absolutely contraindicated) due to the risk of paraphimosis and priapism. [ 6 ] Acepromazine also lowers blood pressure, and should therefore be used with caution in horses that are experiencing anemia , dehydration , shock , or colic .
In dogs, sheep, horses, and cattle, the half-life is very short: only 1.21– 5.97 minutes. Complete elimination of the drug can take up to 23 minutes in sheep and up to 49 minutes in horses. [1] [3] In young rats the half-life is one hour. [18] Xylazine has a large volume of distribution of V d = 1.9 – 2.5 for horses, cattle, sheep, and dogs ...
It is a local anesthetic, astringent and deodorant and has antiplaque effects. [ 1 ] Hexetidine is the medicinal ingredient in Sterisol , which is labelled for the symptomatic treatment of: streptococcal pharyngitis ('strep throat'), tonsillitis , pharyngitis , laryngitis , gingivitis , ulcerative stomatitis , oral thrush and Vincent's angina ...
Side effects may include irritation of the skin and discoloration of clothing. [2] If it is taken by mouth, toxicity and death may occur. [4] Potassium permanganate is an oxidizing agent. [5] The British National Formulary recommends that each 100 mg be dissolved in a liter of water before use. [3]
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