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Tumors with these characteristics are regarded as a subtype of IMT termed epithelioid inflammatory myofibroblastic sarcoma (EIMS). [ 3 ] [ 11 ] [ 12 ] The tumors in IMT and EIMS consistently contain pro-inflammatory white blood cells and in most cases tumor cells that express highly abnormal oncogenic (cancer-causing) fusion proteins such as ...
Dermatofibrosarcoma protuberans, fibrosarcomatous, also termed fibrosarcomatous dermatofibrosarcoma protuberans (or fibrosarcomatous DFSP), is a more aggressive tumor than dermatofibrosarcoma protuberans tumors). [29] Solitary fibrous tumour, also fibrous termed tumor of the pleura. [30] Inflammatory myofibroblastic tumour [31]
Other names associated with plasma cell granulomas are inflammatory myofibroblastic tumor, inflammatory myofibrohistiocytic tumor, benign myofibroblastoma, pseudosarcoma, fibrous histocytoma, fibroxanthoma, xanthomatous pseudotumor, xanthogranuloma, myxoid hamartoma, and lymphoid hamartoma. [1] [2] [4] [7] [8] [9]
Acral myxoinflammatory fibroblastic sarcoma (AMSF), also termed myxoinflammatory fibroblastic sarcoma (MSF), is a rare, low-grade, soft tissue tumor that the World Health Organization (2020) classified as in the category of rarely metastasizing fibroblastic and myofibroblastic tumors. [1]
NF may resemble and therefore be misdiagnosed as dermatofibrosarcoma protuberans, fibrosarcoma, malignant fibrous histiocytoma, spindle-cell melanoma, [27] leiomyosarcoma, [4] or inflammatory myofibroblastic tumor. [8] The diagnosis of NF and its variants depends on a combination of findings, no single one of which is definitive.
Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) might share several aspects of the XP. Likewise there might be some superimpositions between the XP and the plasma cell granuloma/histiocytoma-inflammatory myofibroblastic tumor complex. [18] [19] The XP might be an important stage of this complex.
A cancer-associated fibroblast (CAF) (also known as tumour-associated fibroblast; carcinogenic-associated fibroblast; activated fibroblast) is a cell type within the tumor microenvironment that promotes tumorigenic features by initiating the remodelling of the extracellular matrix or by secreting cytokines.
However its tumors have a distinctly different clinical presentation and histopathology than IMF. [24] The World Health Organization (2020) redefined infantile digital fibromatosis as a benign tumor in the category of benign fibroblastic and myofibroblastic tumors and therefore different than IMF. [25]
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