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phenylpropanolamine – controls urinary incontinence in dogs; phenytoin/pentobarbital – animal euthanasia product containing phenytoin and pentobarbital; pimobendan – phosphodiesterase 3 inhibitor used to manage heart failure in dogs; pirlimycin – antimicrobial; ponazuril – anticoccidial
Maropitant (INN; [3] brand name: Cerenia, used as maropitant citrate , is a neurokinin-1 (NK 1) receptor antagonist developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs. It was approved by the FDA in 2007, for use in dogs [4] [5] and in 2012, for cats. [6]
While it is not entirely clear how it works, it is believed to function by dilating blood vessels. [1] Nitroglycerin was written about as early as 1846 [5] [6] and came into medical use in 1878. [7] [8] [9] The drug nitroglycerin is a dilute form of the same chemical used as the explosive, nitroglycerin. [9] Dilution makes it non-explosive. [9]
Nitroglycerin (NG) (alternative spelling of nitroglycerine), also known as trinitroglycerol (TNG), nitro, glyceryl trinitrate (GTN), or 1,2,3-trinitroxypropane, is a dense, colorless or pale yellow, oily, explosive liquid most commonly produced by nitrating glycerol with white fuming nitric acid under conditions appropriate to the formation of the nitric acid ester.
Pimobendan is indicated for the management of the signs of mild, moderate, or severe congestive heart failure in dogs due to clinical myxomatous mitral valve disease (MMVD) or dilated cardiomyopathy (DCM); [1] [7] and for use with concurrent therapy for congestive heart failure (e.g.,furosemide, etc.) as appropriate on a case-by-case basis. [1]
The drug, branded as Credelio Quattro, is a single, monthly chewable tablet for dogs eight weeks of age or older, the company said. The drug is approved for the treatment of flea and tick ...
Alpha-, beta-, and gamma-cyclodextrin are all generally recognized as safe by the U.S. FDA. [3] [4] They have been applied for delivery of a variety of drugs, including hydrocortisone, prostaglandin, nitroglycerin, itraconazole, chloramphenicol.
The primary use is in the form of nitroglycerin, either pill or liquid spray forms, which, as a prodrug, is denitrated and releases the active metabolite nitric oxide (NO). As with all supplements of nitric oxide, the response is short-lived because, as a normally produced internal physiologic control mechanism, increased concentrations lead to ...
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