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Isopropyl myristate is a polar emollient and is used in cosmetic and topical pharmaceutical preparations where skin absorption is desired. It is also used as a treatment for head lice. [2] It is also in flea and tick killing products for pets.
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Myristic acid (IUPAC name: tetradecanoic acid) is a common saturated fatty acid with the molecular formula CH 3 (CH 2) 12 COOH.Its salts and esters are commonly referred to as myristates or tetradecanoates.
In 1982, Koiti Titani's lab identified an "N-terminal blocking group" on the catalytic subunit of cyclic AMP-dependent protein kinase in cows as n-tetradecanoyl. [6]Almost simultaneously in Claude B. Klee's lab, this same N-terminal blocking group was further characterized as myristic acid. [7]
12-O-Tetradecanoylphorbol-13-acetate (TPA), also commonly known as tetradecanoylphorbol acetate, tetradecanoyl phorbol acetate, and phorbol 12-myristate 13-acetate (PMA) is a diester of phorbol. It is a potent tumor promoter often employed in biomedical research to activate the signal transduction enzyme protein kinase C (PKC).
Isopropylamine can be obtained by reaction of isopropyl alcohol with ammonia in presence of a catalyst: [3] (CH 3) 2 CHOH + NH 3 → (CH 3) 2 CHNH 2 + H 2 O. Isopropylamine is a building block for the preparation of many herbicides and pesticides including atrazine, bentazon, glyphosate, imazapyr, ametryne, desmetryn, prometryn, pramitol, dipropetryn, propazine, fenamiphos, and iprodione. [3]
An ester of carboxylic acid.R stands for any group (organic or inorganic) and R′ stands for organyl group.. In chemistry, an ester is a compound derived from an acid (organic or inorganic) in which the hydrogen atom (H) of at least one acidic hydroxyl group (−OH) of that acid is replaced by an organyl group (−R).
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